5-Amino-1MQ

Description

For Research Use Only. This product is supplied exclusively for laboratory research and is not intended for human or veterinary use.

5-Amino-1MQ Iodide Research Compound

5-Amino-1MQ is a small-molecule enzyme inhibitor, not a peptide. The supplied research form is identified as 5-amino-1-methylquinolinium iodide, a selective inhibitor of nicotinamide N-methyltransferase (NNMT).

Research has used it to probe NNMT-dependent nicotinamide and methyl-donor pathways in cells and rodent models. It is not an NAD+ precursor and should not be described as if it directly supplies NAD+.

Technical Specifications

Product	5-Amino-1MQ iodide
Full chemical name	5-Amino-1-methylquinolinium iodide
Compound class	Small-molecule NNMT inhibitor
Chemical formula	C10H11IN2
Molecular weight	286.11 g/mol (iodide salt)
CAS number	42464-96-0
Purity	Above 99% by third-party HPLC testing
Physical form	Solid research material; colour may range from faint red to brown
Available format	5mg
Intended use	Laboratory research and analytical use only

Independent Batch Testing

Every current ZENTRA 5-Amino-1MQ batch is independently tested and records an HPLC purity result above 99%. Use the batch number printed on the product label to locate the corresponding third-party report in our Batch Verification and COA Centre. Researchers should consult the individual report for the exact analytical methods, result and testing date for their supplied batch.

5-Amino-1MQ Research Context

Medicinal-chemistry research identified membrane-permeable quinolinium NNMT inhibitors and evaluated 5-amino-1MQ in enzyme assays, cell systems and diet-induced-obesity mouse models.

The findings are preclinical and do not establish human safety or efficacy. Because salt form changes molecular weight and handling properties, researchers should use the iodide-salt values and consult the batch COA.

Storage and Handling

Store the unopened iodide salt at approximately -20°C, protected from light and moisture. Use a validated laboratory solvent and stability protocol appropriate to the iodide salt; bacteriostatic water is not a universal default.

5-Amino-1MQ Research FAQs

Is 5-Amino-1MQ a peptide?

No. It is a quinolinium small molecule and does not have an amino-acid sequence.

What enzyme does it inhibit?

Published research characterises it as an inhibitor of nicotinamide N-methyltransferase, or NNMT.

Is it an NAD+ precursor?

No. It is studied for indirect effects on nicotinamide and methylation pathways through NNMT inhibition.

Why does the salt form matter?

The iodide counter-ion changes the molecular formula and weight. The iodide salt is approximately 286.11 g/mol.

How is purity checked?

The current batch is independently HPLC tested above 99% and matched to an online batch report.

Is it intended for human use?

No. It is supplied only for controlled laboratory research.

Selected Scientific Sources

1. Selective and membrane-permeable small-molecule inhibitors of NNMT.
2. PubChem record for 5-amino-1-methylquinolinium iodide.
3. Review of NNMT in obesity and metabolic research.

Research Resources

• NAD+ Research Compound
• SLU-PP-332 Research Compound
• Batch Verification and COAs
• Research Compound Storage Guide
• Browse All Research Peptides

For research use only. Not for human or veterinary use.