CJC-1295 with DAC

Description

For Research Use Only. This product is supplied exclusively for laboratory research and is not intended for human or veterinary use.

CJC-1295 with DAC Research Peptide

CJC-1295 with DAC is a long-acting GHRH analogue built from a tetrasubstituted GRF(1-29) core plus a C-terminal lysine carrying a maleimidopropionyl drug-affinity-complex group. ZENTRA supplies it as high-purity lyophilised research material in a 5mg format.

The DAC group was designed to react with free thiol groups on circulating proteins such as albumin. This structure is chemically distinct from the 29-amino-acid material commonly sold as “CJC-1295 without DAC” or modified GRF(1-29).

Technical Specifications

Independent Batch Testing

Every current ZENTRA CJC-1295 with DAC batch is independently tested and records an HPLC purity result above 99%. The batch number on the product label can be checked against the corresponding third-party report in our Batch Verification and COA Centre. Researchers should consult the individual report for the exact analytical methods, result and testing date for their supplied batch.

CJC-1295 with DAC Research Context

The original development study examined albumin bioconjugation, GHRH-receptor activity and pharmacokinetics in rats, reporting prolonged detectability compared with unmodified GRF(1-29). A subsequent small randomized study in healthy adults examined pharmacokinetics and GH/IGF-I responses, estimating a multi-day half-life. Later experimental work investigated serum-protein changes after GH/IGF-1-axis activation.

These studies are limited and do not establish an approved use or long-term safety. They apply to the DAC compound and must not be presented as evidence for modified GRF(1-29) without DAC.

Storage and Handling

For long-term storage, keep unopened lyophilised material at approximately -20°C. For short-term laboratory storage, maintain at 2-8°C. Protect the vial from light, moisture and repeated temperature changes. Use appropriate laboratory handling procedures and consult your institutional protocol before preparing research solutions.

CJC-1295 with DAC Research FAQs

What does DAC mean?

DAC stands for drug affinity complex. In CJC-1295 it refers to the maleimide-containing modification designed for covalent binding to circulating proteins such as albumin.

Is CJC-1295 with DAC the same as modified GRF(1-29)?

No. They share a tetrasubstituted GHRH analogue core, but the DAC compound includes an additional modified lysine and has a higher molecular mass.

Which size is available?

This product is supplied as 5mg of lyophilised research material.

What has published research examined?

Published work has examined albumin binding, receptor activity, pharmacokinetics and GH/IGF-I signalling. The evidence base is limited and does not establish an approved therapeutic use.

How is purity verified?

Every current batch is independently HPLC tested above 99% purity with online batch-level COA verification.

Is this product intended for human or veterinary use?

No. It is supplied strictly for laboratory research and analytical purposes.

Selected Primary Research

1. Identification of CJC-1295 as a long-lasting albumin-binding GRF analogue.
2. Pharmacokinetic and GH/IGF-I study of CJC-1295 in healthy adults.
3. Serum protein-profile changes after experimental CJC-1295 exposure.

Research Resources

• CJC-1295 without DAC
• Ipamorelin Research Peptide
• Batch Verification and COAs
• Research Peptide Storage Guide
• Lyophilised Research Material Preparation Guide
• Browse All Research Peptides

For research use only. Not for human or veterinary use.

Read our research guide comparing CJC-1295 with DAC and without DAC.